SAA

Serum amyloid A (SAA) is a precursor of tissue amyloid A, similar to C-reactive protein (CRP), an acute-phase reactive protein produced by liver cells. SAA exists in a constant amount in the serum of normal people, but SAA can increase hundreds to thousands of times within 48-72h in the acute phase of inflammation or infection, and it decreases rapidly in the recovery phase of the disease. It is a more sensitive diagnosis than CRP. A marker of bacterial or viral infection.

Clinical significance

1. Prompt inflammatory response and identify the type of infection;

2. A strong marker of cardiovascular mortality;

3. Sensitive markers for monitoring transplant rejection;

4. Early diagnosis and identification of infectious diseases in children.

Profile of SAA